Histological grading and prognosis in breast cancer: a study of 1409 cases of which 359 have been followed for 15 years

HJG Bloom, WW Richardson - British journal of cancer, 1957 - ncbi.nlm.nih.gov
HJG Bloom, WW Richardson
British journal of cancer, 1957ncbi.nlm.nih.gov
THERE is still no general agreement as to the most suitable method of treating operable
carcinoma of the breast. We believe that the difficultes in assessing the relative merits of
greater and lesser surgical procedures, and the value of radiotherapy in these cases is
largely dueto the comparison of resultsin groups ofpatients which are not strictly
comparable. There is great variation in the progress of cases of breast cancer even in
patients of the same age, with the same duration of symptoms, and with tumnours of com …
THERE is still no general agreement as to the most suitable method of treating operable carcinoma of the breast. We believe that the difficultes in assessing the relative merits of greater and lesser surgical procedures, and the value of radiotherapy in these cases is largely dueto the comparison of resultsin groups ofpatients which are not strictly comparable.
There is great variation in the progress of cases of breast cancer even in patients of the same age, with the same duration of symptoms, and with tumnours of com-parable clinical extent. Women with advanced disease and a long history may survive for many years followingonly limited treatment, whilst some patients who attend hospital early with what appears to be a localised growth, may die of metastases within twelve months of radical surgery and a full course of post-
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