Mast cells (MCs) are traditionally thought of as a nuisance for its host, for example, by
causing many of the symptoms associated with allergic reactions. In addition, recent
research has put focus on MCs for displaying harmful effects during various autoimmune
disorders. On the other hand, MCs can also be beneficial for its host, for example, by
contributing to the defense against insults such as bacteria, parasites, and snake venom
toxins. When the MC is challenged by an external stimulus, it may respond by degranulation …