[HTML][HTML] Cholecystokinin-A receptors are involved in food intake suppression in rats after intake of all fats and carbohydrates tested

N Bellissimo, GH Anderson - The Journal of nutrition, 2003 - Elsevier
The hypothesis of these studies was that all fats and carbohydrates suppress food intake, at
least in part, via cholecystokinin-A receptors (CCKAR). Fat (coconut oil, beef tallow, olive
and safflower oil) and carbohydrate (cornstarch, sucrose, glucose and fructose) preloads
were given intragastrically (1 g/4 mL) 30 min before feeding. Devazepide (0.25 mg/kg), a
CCKAR antagonist, was given intraperitoneally at 60 or 30 min before or with each of the
macronutrient preloads. Devazepide reversed food intake suppression caused by all fat and …