Heterogeneous cardiac proteasomes: mandated by diverse substrates?
SB Scruggs, P Ping, C Zong - Physiology, 2011 - journals.physiology.org
SB Scruggs, P Ping, C Zong
Physiology, 2011•journals.physiology.orgProteasome biology has taken central stage in cardiac physiology and pathophysiology. The
molecular heterogeneity of proteasome subpopulations supports the specificity of
proteasome function to degrade diverse substrate repertoires. Unveiling the dynamics of
proteasome function should inspire new therapeutic strategies for combating cardiac
disease.
molecular heterogeneity of proteasome subpopulations supports the specificity of
proteasome function to degrade diverse substrate repertoires. Unveiling the dynamics of
proteasome function should inspire new therapeutic strategies for combating cardiac
disease.
Proteasome biology has taken central stage in cardiac physiology and pathophysiology. The molecular heterogeneity of proteasome subpopulations supports the specificity of proteasome function to degrade diverse substrate repertoires. Unveiling the dynamics of proteasome function should inspire new therapeutic strategies for combating cardiac disease.
American Physiological Society