Novel pharmacotherapeutic approaches for the treatment of drug addiction and craving

CA Heidbreder, JJ Hagan - Current opinion in pharmacology, 2005 - Elsevier
Pharmacological agents have shown limited efficacy and consistency in the treatment of
drug addiction. Hence, the development of new medications with improved long-term
efficacy and reduced side effects should be given a high priority given the costs to society
associated with drug abuse and drug-related pathologies. Neurochemical systems can be
significantly altered by repeated exposure to drugs of abuse. These long-term molecular and
neurochemical changes might, in turn, explain the core features of addiction—the …