Renal electrolyte effects of guanylin and uroguanylin

A Sindic, E Schlatter - Current opinion in nephrology and …, 2007 - journals.lww.com
A Sindic, E Schlatter
Current opinion in nephrology and hypertension, 2007journals.lww.com
Mechanisms and sites of renal actions of guanylin peptides are still not completely
understood. Renal receptors for guanylin peptides are probably G-protein-coupled. The
influences of guanylin peptides on natriuresis, kaliuresis, and diuresis are complex and only
further detailed studies will allow a complete understanding of the function of these peptides.
Summary
Mechanisms and sites of renal actions of guanylin peptides are still not completely understood. Renal receptors for guanylin peptides are probably G-protein-coupled. The influences of guanylin peptides on natriuresis, kaliuresis, and diuresis are complex and only further detailed studies will allow a complete understanding of the function of these peptides.
Lippincott Williams & Wilkins