[HTML][HTML] The role of thrombin activatable fibrinolysis inhibitor in arterial thrombosis at a young age: the ATTAC study

ELE De Bruijne, A Gils, AHC Guimarães… - Journal of Thrombosis …, 2009 - Elsevier
Background and objectives: Thrombin activatable fibrinolysis inhibitor (TAFI) attenuates
fibrinolysis and may therefore contribute to the pathophysiology of arterial thrombosis. The
aim of the present study was to elucidate the pathogenetic role of TAFI levels and genotypes
in young patients with arterial thrombosis. Patients and methods: In a case–control study,
327 young patients with a recent first-ever event of coronary heart disease (CHD subgroup)
or cerebrovascular disease (ischemic stroke subgroup) and 332 healthy young controls …