Loss of Thy-1 (CD90) antigen expression on mesenchymal stromal cells from hematologic malignancies is induced by in vitro angiogenic stimuli and is associated …
D Campioni, F Lanza, S Moretti, L Ferrari, A Cuneo - Cytotherapy, 2008 - Elsevier
Background Little is known about human mesenchymal stromal cell (hMSC) phenotypic and
functional subsets in response to environmental stimuli. The strategy used in this study
focused on defining hMSC functional subpopulations based in particular on their Thy-1
(CD90) antigen (Ag) surface expression. Methods The effect of different in vitro
microenvironmental conditions on the isolation and expansion of bone marrow-derived (BM)
hMSC from hematologic malignancies (HM) and normal samples (NS) was assayed. hMSC …
functional subsets in response to environmental stimuli. The strategy used in this study
focused on defining hMSC functional subpopulations based in particular on their Thy-1
(CD90) antigen (Ag) surface expression. Methods The effect of different in vitro
microenvironmental conditions on the isolation and expansion of bone marrow-derived (BM)
hMSC from hematologic malignancies (HM) and normal samples (NS) was assayed. hMSC …