Neuropsychological profile of autism and the broad autism phenotype

M Losh, R Adolphs, MD Poe, S Couture… - Archives of general …, 2009 - jamanetwork.com
Context Multiple articles describe a constellation of language, personality, and social-
behavioral features present in relatives that mirror the symptom domains of autism, but are
much milder in expression. Studies of this broad autism phenotype (BAP) may provide a
potentially important complementary approach for detecting the genes causing autism and
defining associated neural circuitry by identifying more refined phenotypes that can be
measured quantitatively in both affected and unaffected individuals and that are tied to …