Lipids in the heart: a source of fuel and a source of toxins

TS Park, H Yamashita, WS Blaner… - Current opinion in …, 2007 - journals.lww.com
TS Park, H Yamashita, WS Blaner, IJ Goldberg
Current opinion in lipidology, 2007journals.lww.com
Genetic modifications that affect lipid uptake, oxidation, and storage are being exploited to
elucidate the pathophysiology of cardiomyopathies and to discover how lipids relate to heart
failure in humans with obesity and diabetes mellitus. This information is likely to lead to new
diagnostic categories of cardiomyopathy and more pathophysiologically appropriate
treatments.
Summary
Genetic modifications that affect lipid uptake, oxidation, and storage are being exploited to elucidate the pathophysiology of cardiomyopathies and to discover how lipids relate to heart failure in humans with obesity and diabetes mellitus. This information is likely to lead to new diagnostic categories of cardiomyopathy and more pathophysiologically appropriate treatments.
Lippincott Williams & Wilkins