Enlarged glomerular size is a feature of focal segmental glomerulosclerosis, obesity-related
glomerulopathy, diabetic nephropathy, and hypertension. The distribution of glomerular
volumes within different cortical zones and glomerular volume alterations with age and
obesity may contribute to understanding the evolution of these diseases. We analyzed the
distributions of volumes of individual glomeruli in the superficial, middle, and juxtamedullary
cortex of normal human kidneys using the disector/Cavalieri method. Volumes (V glom) of …