Phosphorus-31 NMR magnetization-transfer measurements of ATP turnover during steady-state isometric muscle contraction in the rat hind limb in vivo
Biochemistry, 1989•ACS Publications
Hz, or increasing the frequency of a 10-ms pulse from 0.5 to 2 Hz resulted in an increase in
the flux which was an approximately linear function of the increase in the tension-time
integral. The flux showed an approximately linear dependence on the calculated free
cytosolic ADP concentration up to an ADP concentration of about 90 µ. The data are
consistent with control of mitochondrial ATP synthesis by the cytosolic ADP concentration
and indicate that the apparent
the flux which was an approximately linear function of the increase in the tension-time
integral. The flux showed an approximately linear dependence on the calculated free
cytosolic ADP concentration up to an ADP concentration of about 90 µ. The data are
consistent with control of mitochondrial ATP synthesis by the cytosolic ADP concentration
and indicate that the apparent
Hz, or increasing the frequency of a 10-ms pulse from 0.5 to 2 Hz resulted in an increase in the flux which was an approximately linear function of the increase in the tension-time integral. The flux showed an approximately linear dependence on the calculated free cytosolic ADP concentration up to an ADP concentration of about 90 µ. The data are consistent with control of mitochondrial ATP synthesis by the cytosolic ADP concentration and indicate that the apparent
ACS Publications