Thrombocytopenia in the sepsis syndrome: role of hemophagocytosis and macrophage colony-stimulating factor
B Francois, F Trimoreau, P Vignon, P Fixe… - The American journal of …, 1997 - Elsevier
BACKGROUND: Thrombocytopenia is frequently encountered in critically ill patients with the
sepsis syndrome, but its mechanisms frequently remain undetermined. Hemophagocytosis
has been reported as a cause of thrombocytopenia in various diseases. This prospective
study was designed to assess:(1) the incidence of hemophagocytosis in patients suffering
from both the sepsis syndrome and unexplained thrombocytopenia, and (2) the circulating
level of the macrophage-colony-stimulating factor (M-CSF) according to the presence or …
sepsis syndrome, but its mechanisms frequently remain undetermined. Hemophagocytosis
has been reported as a cause of thrombocytopenia in various diseases. This prospective
study was designed to assess:(1) the incidence of hemophagocytosis in patients suffering
from both the sepsis syndrome and unexplained thrombocytopenia, and (2) the circulating
level of the macrophage-colony-stimulating factor (M-CSF) according to the presence or …