Hypercytokinemia in hemophagocytic syndrome
F Fujiwara, S Hibi, S Imashuku - Journal of Pediatric Hematology …, 1993 - journals.lww.com
Purpose: The study was performed to clarify in the hemophagocytic syndrome (HPS) how
cytokinemia plays a role in its pathogenesis and if cytokinemia is of prognostic value.
Patients and Methods: Serum concentrations of ferritin, interferon (IFN)-y, soluble interleukin-
2 (IL-2) receptor, IL-6, and other cytokines were determined during the acute phase of the
HPS in 29 children and three adults. Data comparing malignancy-associated (MAHS; n= 17)
and infection-associated hemophagocytic syndrome (IAHS; n= 15) and those comparing …
cytokinemia plays a role in its pathogenesis and if cytokinemia is of prognostic value.
Patients and Methods: Serum concentrations of ferritin, interferon (IFN)-y, soluble interleukin-
2 (IL-2) receptor, IL-6, and other cytokines were determined during the acute phase of the
HPS in 29 children and three adults. Data comparing malignancy-associated (MAHS; n= 17)
and infection-associated hemophagocytic syndrome (IAHS; n= 15) and those comparing …