[HTML][HTML] Thematic review series: patient-oriented research. Free fatty acid metabolism in human obesity

C Koutsari, MD Jensen - Journal of lipid research, 2006 - ASBMB
Adipose tissue lipolysis provides circulating FFAs to meet the body's lipid fuel demands. FFA
release is well regulated in normal-weight individuals; however, in upper-body obesity,
excess lipolysis is commonly seen. This abnormality is considered a cause for at least some
of the metabolic defects (dyslipidemia, insulin resistance) associated with upper-body
obesity." Normal" lipolysis is sex-specific and largely determined by the individual's resting
metabolic rate. Women have greater FFA release rates than men without higher FFA …