[HTML][HTML] Adipocyte protein S3-12 coats nascent lipid droplets

NE Wolins, JR Skinner, MJ Schoenfish… - Journal of Biological …, 2003 - ASBMB
Most animals store lipid intracellularly in protein-coated droplets. The protein coat usually
contains at least one member of the PAT (perilipin, adipose differentiation-related protein,
and TIP47) family. Evidence suggests that PAT proteins control access to the lipid they
enclose. The protein S3-12, which has sequence similarity to the PAT proteins, was found in
a screen for adipocyte-specific proteins. The adipocyte expression of S3-12 and its similarity
to the PAT proteins suggest that S3-12 is involved in adipocyte lipid storage. To test this …