[HTML][HTML] 17β-estradiol protects against oxidative stress-induced cell death through the glutathione/glutaredoxin-dependent redox regulation of Akt in myocardiac H9c2 …
Y Urata, Y Ihara, H Murata, S Goto, T Koji… - Journal of Biological …, 2006 - ASBMB
The GSH/glutaredoxin (GRX) system is involved in the redox regulation of certain enzyme
activities, and this system protects cells from H 2 O 2-induced apoptosis by regulating the
redox state of Akt (Murata, H., Ihara, Y., Nakamura, H., Yodoi, J., Sumikawa, K., and Kondo,
T.(2003) J. Biol. Chem. 278, 50226–50233). Estrogens, such as 17β-estradiol (E 2), play an
important role in development, growth, and differentiation and appear to have protective
effects on oxidative stress mediated by estrogen receptor α (ERα). However, the role of the …
activities, and this system protects cells from H 2 O 2-induced apoptosis by regulating the
redox state of Akt (Murata, H., Ihara, Y., Nakamura, H., Yodoi, J., Sumikawa, K., and Kondo,
T.(2003) J. Biol. Chem. 278, 50226–50233). Estrogens, such as 17β-estradiol (E 2), play an
important role in development, growth, and differentiation and appear to have protective
effects on oxidative stress mediated by estrogen receptor α (ERα). However, the role of the …