Fibulins: physiological and disease perspectives

WS Argraves, LM Greene, MA Cooley… - EMBO …, 2003 - embopress.org
WS Argraves, LM Greene, MA Cooley, WM Gallagher
EMBO reports, 2003embopress.org
The fibulins are a family of proteins that are associated with basement membranes and
elastic extracellular matrix fibres. This review summarizes findings from studies of animal
models of fibulin deficiency, human fibulin gene mutations, human tumours and injury
models that have advanced our understanding of the normal and pathological roles of
members of this formerly obscure family.
The fibulins are a family of proteins that are associated with basement membranes and elastic extracellular matrix fibres. This review summarizes findings from studies of animal models of fibulin deficiency, human fibulin gene mutations, human tumours and injury models that have advanced our understanding of the normal and pathological roles of members of this formerly obscure family.
embopress.org