The effect of imatinib on cytomegalovirus reactivation in hematopoietic cell transplantation

G Travi, SA Pergam, H Xie, P Carpenter… - Clinical Infectious …, 2009 - academic.oup.com
G Travi, SA Pergam, H Xie, P Carpenter, HP Kiem, L Corey, MJ Boeckh
Clinical Infectious Diseases, 2009academic.oup.com
In vitro studies have shown possible antiviral effects of tyrosine kinase inhibitors. In a
retrospective study, we show that use of the tyrosine kinase inhibitor imatinib does not
appear to reduce cytomegalovirus reactivation during the first 100 days after transplantation
in a cohort of hematopoietic cell transplant recipients.
Abstract
In vitro studies have shown possible antiviral effects of tyrosine kinase inhibitors. In a retrospective study, we show that use of the tyrosine kinase inhibitor imatinib does not appear to reduce cytomegalovirus reactivation during the first 100 days after transplantation in a cohort of hematopoietic cell transplant recipients.
Oxford University Press