Imbalance in intestinal microflora constitution could be involved in the pathogenesis of inflammatory bowel disease
H Takaishi, T Matsuki, A Nakazawa, T Takada… - International Journal of …, 2008 - Elsevier
Since genetically engineered animal models of inflammatory bowel disease (IBD) do not
develop colitis under germ-free conditions, the intestinal microflora is thought to be one of
the most important environmental factors associated with IBD. To understand the
involvement of intestinal microflora in the pathogenesis of IBD, we analyzed the constituents
of intestinal microflora in IBD. Faecal samples from 73 patients with ulcerative colitis (UC)
and 23 patients with Crohn's disease (CD) were analyzed by quantitative PCR using 16S …
develop colitis under germ-free conditions, the intestinal microflora is thought to be one of
the most important environmental factors associated with IBD. To understand the
involvement of intestinal microflora in the pathogenesis of IBD, we analyzed the constituents
of intestinal microflora in IBD. Faecal samples from 73 patients with ulcerative colitis (UC)
and 23 patients with Crohn's disease (CD) were analyzed by quantitative PCR using 16S …