Loss of CD117 (c-kit)-and CD34-positive ICC and associated CD34-positive fibroblasts defines a subpopulation of chronic intestinal pseudo-obstruction
CJ Streutker, JD Huizinga, F Campbell… - The American journal …, 2003 - journals.lww.com
Chronic idiopathic intestinal pseudo-obstruction is a syndrome in which symptoms of
intestinal obstruction are present in the absence of mechanical obstruction. Lack of normal
pacemaker activity, usually generated by the interstitial cells of Cajal (ICC), could account for
the apparent obstruction. ICC are normally located around and between the myenteric
plexus ganglia and within muscle and also in the deep muscular plexus of the small bowel
and the submuscular plexus of the large intestine, just within the circular muscle. ICC can be …
intestinal obstruction are present in the absence of mechanical obstruction. Lack of normal
pacemaker activity, usually generated by the interstitial cells of Cajal (ICC), could account for
the apparent obstruction. ICC are normally located around and between the myenteric
plexus ganglia and within muscle and also in the deep muscular plexus of the small bowel
and the submuscular plexus of the large intestine, just within the circular muscle. ICC can be …