Utility of food-specific IgE concentrations in predicting symptomatic food allergy
HA Sampson - Journal of Allergy and Clinical Immunology, 2001 - Elsevier
Background: The double-blind, placebo-controlled food challenge is considered the gold
standard for diagnosing food allergy. However, in a retrospective analysis of children and
adolescents with atopic dermatitis and food allergy, discrete food-specific IgE concentrations
were established that could predict clinical reactivity to egg, milk, peanut, and fish with
greater than 95% certainty. Objective: The purpose of this investigation was to determine the
utility of these 95% predictive decision points in a prospective evaluation of food allergy …
standard for diagnosing food allergy. However, in a retrospective analysis of children and
adolescents with atopic dermatitis and food allergy, discrete food-specific IgE concentrations
were established that could predict clinical reactivity to egg, milk, peanut, and fish with
greater than 95% certainty. Objective: The purpose of this investigation was to determine the
utility of these 95% predictive decision points in a prospective evaluation of food allergy …