Correlation of IgE/IgG4 milk epitopes and affinity of milk-specific IgE antibodies with different phenotypes of clinical milk allergy
J Wang, J Lin, L Bardina, M Goldis… - Journal of Allergy and …, 2010 - Elsevier
BACKGROUND: Results from large-scale epitope mapping with a peptide microarray have
been shown to correlate with clinical features of milk allergy. OBJECTIVES: We sought to
assess IgE and IgG4 epitope diversity and IgE affinity in different clinical phenotypes of milk
allergy and identify informative epitopes that might be predictive of clinical outcomes of milk
allergy. METHODS: Forty-one subjects were recruited from a larger study on the effects of
ingesting heat-denatured milk proteins in subjects with milk allergy. Using food challenges …
been shown to correlate with clinical features of milk allergy. OBJECTIVES: We sought to
assess IgE and IgG4 epitope diversity and IgE affinity in different clinical phenotypes of milk
allergy and identify informative epitopes that might be predictive of clinical outcomes of milk
allergy. METHODS: Forty-one subjects were recruited from a larger study on the effects of
ingesting heat-denatured milk proteins in subjects with milk allergy. Using food challenges …