[PDF][PDF] Clinical safety of high oral doses of acetylcysteine

LF Miller, BH Rumack - Semin Oncol, 1983 - academia.edu
RECENT nationwide, multiclinic evalua-tion of N-acetylcysteine (NAC)(Mucomystº) in the
treatment of acetaminophen (APAP) overdose provided useful information for assessing the
safety of this chemoprotective agent. McNeil Consumer Products Company sponsored this
study, which was initiated in 1976 and conducted by the Rocky Mountain Poison Center
under the direction of one of us (BHR) in collaboration with physicians throughout the
country. There were no restrictions placed on patient entry provided the patients agreed to …