High-dose creatine therapy for Huntington disease: a 2-year clinical and MRS study

SJ Tabrizi, AM Blamire, DN Manners, B Rajagopalan… - Neurology, 2005 - AAN Enterprises
SJ Tabrizi, AM Blamire, DN Manners, B Rajagopalan, P Styles, AHV Schapira, TT Warner
Neurology, 2005AAN Enterprises
Methods. Thirteen patients with genetically confirmed HD (including three unaffected) and
four age-matched normal spouse control subjects were recruited to the trial at baseline as
previously described. 6 Patients took 10 g/day of creatine powder (SKB Pharmaceuticals,
UK) dissolved in orange juice. Biochemical and hematology screening was performed every
3 months.
Methods.
Thirteen patients with genetically confirmed HD (including three unaffected) and four age-matched normal spouse control subjects were recruited to the trial at baseline as previously described. 6 Patients took 10 g/day of creatine powder (SKB Pharmaceuticals, UK) dissolved in orange juice. Biochemical and hematology screening was performed every 3 months.
American Academy of Neurology