[PDF][PDF] Replication-competent retrovirus vectors for cancer gene therapy

CK Tai, N Kasahara - Front Biosci, 2008 - article.imrpress.com
CK Tai, N Kasahara
Front Biosci, 2008article.imrpress.com
Introduction: replication-competent viruses as oncolytic agents 3. MLV-based RCR vectors
for cancer virotherapy: advantages 3.1. Absolute requirement for cell division in order to
propagate 3.2. Non-lytic replication, stable integration, and reduced immunogenicity 3.3.
Regulatable cell killing through stable transfer of suicide genes 3.4. Efficient replication and
gene transfer to cancer cells 4. RCR vectors for cancer virotherapy: potential hazards and
safety considerations 4.1. Potential hazards
Abstract
Introduction: replication-competent viruses as oncolytic agents 3. MLV-based RCR vectors for cancer virotherapy: advantages 3.1. Absolute requirement for cell division in order to propagate 3.2. Non-lytic replication, stable integration, and reduced immunogenicity 3.3. Regulatable cell killing through stable transfer of suicide genes 3.4. Efficient replication and gene transfer to cancer cells 4. RCR vectors for cancer virotherapy: potential hazards and safety considerations 4.1. Potential hazards
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