Leptin in reproduction
S Blüher, CS Mantzoros - Current Opinion in Endocrinology …, 2007 - journals.lww.com
S Blüher, CS Mantzoros
Current Opinion in Endocrinology, Diabetes and Obesity, 2007•journals.lww.comRecent proof-of-concept studies involving leptin administration to humans underline the
critical role of leptin not only in regulating energy homeostasis, but also in maintaining
normal reproductive function. Leptin-replacement therapy is currently under intensive
investigation as a potential novel therapeutic option for several conditions associated with
reproductive dysfunction due to hypoleptinemia.
critical role of leptin not only in regulating energy homeostasis, but also in maintaining
normal reproductive function. Leptin-replacement therapy is currently under intensive
investigation as a potential novel therapeutic option for several conditions associated with
reproductive dysfunction due to hypoleptinemia.
Summary
Recent proof-of-concept studies involving leptin administration to humans underline the critical role of leptin not only in regulating energy homeostasis, but also in maintaining normal reproductive function. Leptin-replacement therapy is currently under intensive investigation as a potential novel therapeutic option for several conditions associated with reproductive dysfunction due to hypoleptinemia.
Lippincott Williams & Wilkins