A haplotype containing quantitative trait loci for SLC1A1 gene expression and its association with obsessive-compulsive disorder
JR Wendland, PR Moya, KR Timpano… - Archives of general …, 2009 - jamanetwork.com
Context Recent evidence from linkage analyses and follow-up candidate gene studies
supports the involvement ofSLC1A1, which encodes the neuronal glutamate transporter, in
the development of obsessive-compulsive disorder (OCD). Objectives To determine the role
of genetic variation ofSLC1A1in OCD in a large case-control study and to better understand
howSLC1A1variation affects functionality. Design A case-control study. Setting Publicly
accessibleSLC1A1expression and genotype data. Patients Three hundred twenty-five OCD …
supports the involvement ofSLC1A1, which encodes the neuronal glutamate transporter, in
the development of obsessive-compulsive disorder (OCD). Objectives To determine the role
of genetic variation ofSLC1A1in OCD in a large case-control study and to better understand
howSLC1A1variation affects functionality. Design A case-control study. Setting Publicly
accessibleSLC1A1expression and genotype data. Patients Three hundred twenty-five OCD …