The pancreas as a single organ: the influence of the endocrine upon the exocrine part of the gland.

JR Henderson, PM Daniel, PA Fraser - Gut, 1981 - ncbi.nlm.nih.gov
JR Henderson, PM Daniel, PA Fraser
Gut, 1981ncbi.nlm.nih.gov
It is tacitlyassumed that the endocrine and exocrine parts of the pancreas are independent of
each other, almost as though they were anatomically related by some sort of celestial
coincidence. What we hope to suggest in this paper is that the two components are
functionally related, and that the endocrine gland exerts a profound effect upon the digestive
activities of the organ. Vascular anatomy of the pancreas In 1882, Kuhne and Lea'noticed
that the pancreas of the living rabbit contained many discrete vascular regions, and they …
It is tacitlyassumed that the endocrine and exocrine parts of the pancreas are independent of each other, almost as though they were anatomically related by some sort of celestial coincidence. What we hope to suggest in this paper is that the two components are functionally related, and that the endocrine gland exerts a profound effect upon the digestive activities of the organ.
Vascular anatomy of the pancreas In 1882, Kuhne and Lea'noticed that the pancreas of the living rabbit contained many discrete vascular regions, and they compared the vessels of these regions with glomerular tufts. It was not until 1893 that Laguesse2 suggested that the vascular regions might be secreting something into the blood which prevented the normal animal from becoming diabetic. He suggested that the vascular areas be called the islets of Langerhans, in memory of their discoverer. 3
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