Plasma granulocyte colony-stimulating factor levels correlate with clinical outcomes in patients with acute lung injury
BT Suratt, MD Eisner, CS Calfee, JB Allard… - Critical care …, 2009 - journals.lww.com
Objectives: To evaluate the association between plasma granulocyte colony-stimulating
factor (G-CSF) levels and clinical outcomes including mortality in patients with acute lung
injury (ALI), and to determine whether lower tidal volume ventilation was associated with a
more rapid decrease in plasma G-CSF over time in patients with ALI. Design: Retrospective
measurement of G-CSF levels in plasma samples that were collected prospectively as part
of a large multicenter clinical trial. Setting: Intensive care units in ten university centers …
factor (G-CSF) levels and clinical outcomes including mortality in patients with acute lung
injury (ALI), and to determine whether lower tidal volume ventilation was associated with a
more rapid decrease in plasma G-CSF over time in patients with ALI. Design: Retrospective
measurement of G-CSF levels in plasma samples that were collected prospectively as part
of a large multicenter clinical trial. Setting: Intensive care units in ten university centers …