Developmentally regulated expression of the regulator of G-protein signaling gene 2 (Rgs2) in the embryonic mouse pituitary
LD Wilson, SA Ross, DA Lepore, T Wada… - Gene expression …, 2005 - Elsevier
During the development of the anterior pituitary gland, five distinct hormone-producing cell
types emerge in a spatially and temporally regulated pattern from an invagination of oral
ectoderm termed Rathke's Pouch. Evidence from mouse knockout and ectopic expression
studies indicates that 12.5 days post coitum (dpc) to 14.5 dpc is a critical period for the
expansion of the progenitor cell pool and the determination of most hormone-secreting cell
types. While signaling proteins and transcription factors have been identified as having key …
types emerge in a spatially and temporally regulated pattern from an invagination of oral
ectoderm termed Rathke's Pouch. Evidence from mouse knockout and ectopic expression
studies indicates that 12.5 days post coitum (dpc) to 14.5 dpc is a critical period for the
expansion of the progenitor cell pool and the determination of most hormone-secreting cell
types. While signaling proteins and transcription factors have been identified as having key …