Chromatin boundaries and chromatin domains
G Felsenfeld, B Burgess-Beusse… - Cold Spring Harbor …, 2004 - symposium.cshlp.org
G Felsenfeld, B Burgess-Beusse, C Farrell, M Gaszner, R Ghirlando, S Huang, C Jin, M Litt…
Cold Spring Harbor symposia on quantitative biology, 2004•symposium.cshlp.orgFigure 1. Two kinds of insulator function.(A) Enhancer blocking: The insulator (I) prevents
Enhancer 1, belonging to gene system 1, from acting inappropriately on Promoter 2 in gene
system 2.(B) Barrier function: The insulator (I) prevents the advance of heterochromatic
regions on the left into transcriptionally active chromatin on the right.
Enhancer 1, belonging to gene system 1, from acting inappropriately on Promoter 2 in gene
system 2.(B) Barrier function: The insulator (I) prevents the advance of heterochromatic
regions on the left into transcriptionally active chromatin on the right.
Figure 1. Two kinds of insulator function.(A) Enhancer blocking: The insulator (I) prevents Enhancer 1, belonging to gene system 1, from acting inappropriately on Promoter 2 in gene system 2.(B) Barrier function: The insulator (I) prevents the advance of heterochromatic regions on the left into transcriptionally active chromatin on the right.
symposium.cshlp.org