ContextPrior intravascular ultrasound (IVUS) trials have demonstrated slowing or halting of
atherosclerosis progression with statin therapy but have not shown convincing evidence of
regression using percent atheroma volume (PAV), the most rigorous IVUS measure of
disease progression and regression. ObjectiveTo assess whether very intensive statin
therapy could regress coronary atherosclerosis as determined by IVUS imaging. Design and
SettingProspective, open-label blinded end-points trial (A Study to Evaluate the Effect of …