[PDF][PDF] Development of a sporozoite malaria vaccine
V Nussenzweig, RS Nussenzweig - Memórias do Instituto Oswaldo …, 1986 - SciELO Brasil
Subsequent studies comparing the structural, immunological and biological properties of CS
proteins showed that they were part of a distinct family of proteins. CS proteins cover
uniformly the surface of the sporozoites and are shed when cross-linked by antibodies. The
studies of Drs. Yoshida, Cochrane and Nardin showed that all CS proteins are synthesized
in large amounts by mature sporozoites. The M, varies between 40 and 60,000 and
isoelectric points under de-naturing conditions between 4 and 5. They have two intracellular …
proteins showed that they were part of a distinct family of proteins. CS proteins cover
uniformly the surface of the sporozoites and are shed when cross-linked by antibodies. The
studies of Drs. Yoshida, Cochrane and Nardin showed that all CS proteins are synthesized
in large amounts by mature sporozoites. The M, varies between 40 and 60,000 and
isoelectric points under de-naturing conditions between 4 and 5. They have two intracellular …