Endothelial progenitor cells in regenerative medicine and cancer: a decade of research
JG Roncalli, J Tongers, MA Renault… - Trends in Biotechnology, 2008 - cell.com
Trends in Biotechnology, 2008•cell.com
Endothelial progenitor cells (EPCs) are a heterogeneous subpopulation of bone marrow
mononuclear cells that have an enhanced potential for differentiation within the endothelial
cell lineage. In response to ischemic injury, EPCs are mobilized from the bone marrow to the
peripheral circulation and home to the sites of new vessel growth, where they become
incorporated into the growing vasculature. Thus, EPCs can be therapeutically useful for
treating ischemic injury or for delivering anti-cancer agents to tumors.
mononuclear cells that have an enhanced potential for differentiation within the endothelial
cell lineage. In response to ischemic injury, EPCs are mobilized from the bone marrow to the
peripheral circulation and home to the sites of new vessel growth, where they become
incorporated into the growing vasculature. Thus, EPCs can be therapeutically useful for
treating ischemic injury or for delivering anti-cancer agents to tumors.
Endothelial progenitor cells (EPCs) are a heterogeneous subpopulation of bone marrow mononuclear cells that have an enhanced potential for differentiation within the endothelial cell lineage. In response to ischemic injury, EPCs are mobilized from the bone marrow to the peripheral circulation and home to the sites of new vessel growth, where they become incorporated into the growing vasculature. Thus, EPCs can be therapeutically useful for treating ischemic injury or for delivering anti-cancer agents to tumors.
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