A unifying hypothesis for the renin–angiotensin system and hematopoiesis: sticking the pieces together with the JAK-STAT pathway
M Arici, Y Büyükaşik - Medical hypotheses, 2000 - Elsevier
JAK-STAT pathway is a recently encountered intracellular signal transduction system. The
pathway is utilized by numerous cytokines, growth factors, and hormones for gene
expression and a variety of biological activities. Hematopoiesis is regulated by many
cytokines and growth factors that support the proliferation and differentiation of progenitor
cells in the bone marrow. JAK-STAT pathway arises as the most common signalling cascade
of a wide range of cytokines and/or growth factors in propagation of physiological and …
pathway is utilized by numerous cytokines, growth factors, and hormones for gene
expression and a variety of biological activities. Hematopoiesis is regulated by many
cytokines and growth factors that support the proliferation and differentiation of progenitor
cells in the bone marrow. JAK-STAT pathway arises as the most common signalling cascade
of a wide range of cytokines and/or growth factors in propagation of physiological and …