Evidence for two distinct classes of unmyelinated nociceptive afferents in monkey

RA Meyer, JN Campbell - Brain research, 1981 - Elsevier
RA Meyer, JN Campbell
Brain research, 1981Elsevier
Unmyelinated nociceptive afferents, responsive to intense mechanical and heat stimuli,
exhibited either a quickly adapting or slowly adapting response to step increases in skin
temperature. These two classes of C fibers were found to differ also in other properties. The
quickly adapting C fibers had significantly lower thresholds to mechanical and heat stimuli,
and smaller receptive field areas than the slowly adapting C fibers.
Abstract
Unmyelinated nociceptive afferents, responsive to intense mechanical and heat stimuli, exhibited either a quickly adapting or slowly adapting response to step increases in skin temperature. These two classes of C fibers were found to differ also in other properties. The quickly adapting C fibers had significantly lower thresholds to mechanical and heat stimuli, and smaller receptive field areas than the slowly adapting C fibers.
Elsevier