Somatosensory perception and function of diffuse noxious inhibitory controls (DNIC) in patients suffering from rheumatoid arthritis

AS Leffler, E Kosek, T Lerndal, B Nordmark… - European Journal of …, 2002 - Elsevier
The purpose was to investigate the influence of ongoing pain from an inflammatory
nociceptive pain with two different disease durations on somatosensory functions and the
effect of heterotopic noxious conditioning stimulation (HNCS) on 'diffuse noxious inhibitory
controls'(DNIC) related mechanisms. Eleven patients with rheumatoid arthritis of a short
duration (< 1 year)(RA1), and 10 patients with rheumatoid arthritis of longer duration (> 5
years)(RA5) as well as 21 age-and sex-matched healthy controls participated. Pressure pain …