Differences in brain responses to visceral pain between patients with irritable bowel syndrome and ulcerative colitis
Patients with mild chronic inflammation of the rectum or ileum have reduced perceptual
responses to rectosigmoid distension compared to patients with irritable bowel syndrome
(IBS). The current study sought to identify differences in regional cerebral blood flow (rCBF)
during rectal distension, which might correspond to these perceptual differences. In 8 male
ulcerative colitis (UC) patients with quiescent disease, 7 male IBS patients and 7 healthy
male controls, rCBF was assessed using 15O-water positron emission tomography at …
responses to rectosigmoid distension compared to patients with irritable bowel syndrome
(IBS). The current study sought to identify differences in regional cerebral blood flow (rCBF)
during rectal distension, which might correspond to these perceptual differences. In 8 male
ulcerative colitis (UC) patients with quiescent disease, 7 male IBS patients and 7 healthy
male controls, rCBF was assessed using 15O-water positron emission tomography at …