N-Acetylaspartate concentrations in the thalami of neuropathic pain patients and healthy comparison subjects measured with 1H-MRS

S Fukui, M Matsuno, T Inubushi, S Nosaka - Magnetic resonance imaging, 2006 - Elsevier
We investigated the absolute concentration of N-acetylaspartate (NAA) in the thalami of
neuropathic pain patients and healthy comparison subjects by single-voxel proton magnetic
resonance spectroscopy (1H-MRS). 1H-MRS was performed with a 1.5-T MR system on a
voxel in the thalamus bilaterally in 9 neuropathic pain patients and 14 healthy control
subjects. We measured the absolute concentration of NAA using a linear combination
model. The NAA concentration in the thalamus decreased significantly on the contralateral …