The TRPC3/6/7 subfamily of cation channels
The mammalian transient receptor potential (TRP) proteins consist of a superfamily of Ca2+-
permeant non-selective cation channels with structural similarities to Drosophila TRP. The
TRP superfamily can be divided into three major families, among them the “canonical TRP”
family (TRPC). The seven protein products of the mammalian TRPC family of genes
(designated TRPC1–7) share in common the activation through PLC-coupled receptors and
have been proposed to encode components of native store-operated channels in different …
permeant non-selective cation channels with structural similarities to Drosophila TRP. The
TRP superfamily can be divided into three major families, among them the “canonical TRP”
family (TRPC). The seven protein products of the mammalian TRPC family of genes
(designated TRPC1–7) share in common the activation through PLC-coupled receptors and
have been proposed to encode components of native store-operated channels in different …
