[HTML][HTML] Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor α-deficient mice

JM Peters, N Hennuyer, B Staels, JC Fruchart… - Journal of Biological …, 1997 - ASBMB
The peroxisome proliferator-activated receptor-α (PPARα) controls gene expression in
response to a diverse class of compounds collectively referred to as peroxisome
proliferators. Whereas most known peroxisome proliferators are of exogenous origin and
include hypolipidemic drugs and other industrial chemicals, several endogenous PPARα
activators have been identified such as fatty acids and steroids. The latter finding and the
fact that PPARα modulates target genes encoding enzymes involved in lipid metabolism …