[HTML][HTML] Regulation of lens fiber cell differentiation by transcription factor c-Maf
S Kawauchi, S Takahashi, O Nakajima, H Ogino… - Journal of Biological …, 1999 - ASBMB
To elucidate the regulatory mechanisms underlying lens development, we searched for
members of the large Maf family, which are expressed in the mouse lens, and found three, c-
Maf, MafB, and Nrl. Of these, the earliest factor expressed in the lens was c-Maf. The
expression of c-Maf was most prominent in lens fiber cells and persisted throughout lens
development. To examine the functional contribution of c-Maf to lens development, we
isolated genomic clones encompassing the murine c-maf gene and carried out its targeted …
members of the large Maf family, which are expressed in the mouse lens, and found three, c-
Maf, MafB, and Nrl. Of these, the earliest factor expressed in the lens was c-Maf. The
expression of c-Maf was most prominent in lens fiber cells and persisted throughout lens
development. To examine the functional contribution of c-Maf to lens development, we
isolated genomic clones encompassing the murine c-maf gene and carried out its targeted …