Leukocyte subpopulations and arteriogenesis: specific role of monocytes, lymphocytes and granulocytes
IE Hoefer, S Grundmann, N van Royen, M Voskuil… - Atherosclerosis, 2005 - Elsevier
OBJECTIVE:: Circulating leukocytes play a crucial role during arteriogenesis. However,
known pro-arteriogenic compounds (MCP-1, GM-CSF) acting via monocytic pathways also
exert positive effects on granulocytes and lymphocytes. The role of these two cell types in
arteriogenesis remains yet to be clarified, which was the aim of the current study.
METHODS:: Ninety New Zealand White Rabbits received either phosphate buffered saline
(PBS), monocyte chemoattractant protein-1 (MCP-1), interleukin-8 (IL-8), neutrophil …
known pro-arteriogenic compounds (MCP-1, GM-CSF) acting via monocytic pathways also
exert positive effects on granulocytes and lymphocytes. The role of these two cell types in
arteriogenesis remains yet to be clarified, which was the aim of the current study.
METHODS:: Ninety New Zealand White Rabbits received either phosphate buffered saline
(PBS), monocyte chemoattractant protein-1 (MCP-1), interleukin-8 (IL-8), neutrophil …