Mechanisms of bacterial pathogenicity

JW Wilson, MJ Schurr, CL LeBlanc… - Postgraduate …, 2002 - academic.oup.com
JW Wilson, MJ Schurr, CL LeBlanc, R Ramamurthy, KL Buchanan, CA Nickerson
Postgraduate medical journal, 2002academic.oup.com
Pathogenic bacteria utilise a number of mechanisms to cause disease in human hosts.
Bacterial pathogens express a wide range of molecules that bind host cell targets to facilitate
a variety of different host responses. The molecular strategies used by bacteria to interact
with the host can be unique to specific pathogens or conserved across several different
species. A key to fighting bacterial disease is the identification and characterisation of all
these different strategies. The availability of complete genome sequences for several …
Abstract
Pathogenic bacteria utilise a number of mechanisms to cause disease in human hosts. Bacterial pathogens express a wide range of molecules that bind host cell targets to facilitate a variety of different host responses. The molecular strategies used by bacteria to interact with the host can be unique to specific pathogens or conserved across several different species. A key to fighting bacterial disease is the identification and characterisation of all these different strategies. The availability of complete genome sequences for several bacterial pathogens coupled with bioinformatics will lead to significant advances toward this goal.
Oxford University Press