Influence of dietary vitamin A on autofluorescence of leupeptin-induced inclusions in the retinal pigment epithelium
ML Katz, M Norberg - Experimental eye research, 1992 - Elsevier
Substantial evidence indicates that the major precursors for retinal pigment epithelial (RPE)
lipofuscin are molecular components of the photoreceptor outer segments. Previous
experiments have demonstrated that the retinoids required for transduction by the
photoreceptors promote RPE lipofuscin fluorophore formation. Animals deficient in these
retinoids accumulate lipofuscin in the RPE at greatly reduced rates. The protein components
of the photoreceptor outer segments also appear to be involved in the formation of RPE …
lipofuscin are molecular components of the photoreceptor outer segments. Previous
experiments have demonstrated that the retinoids required for transduction by the
photoreceptors promote RPE lipofuscin fluorophore formation. Animals deficient in these
retinoids accumulate lipofuscin in the RPE at greatly reduced rates. The protein components
of the photoreceptor outer segments also appear to be involved in the formation of RPE …