That regulatory T cells (Tregs) have a crucial role in controlling allergic diseases such as
asthma is now undisputed. The cytokines most commonly implicated in Treg-mediated
suppression of allergic asthma are transforming growth factor-β (TGF-β) and interleukin (IL)-
10). In addition to naturally occurring Tregs, adaptive Tregs, induced in response to foreign
antigens, have been shown in recent studies. The concept of inducible/adaptive Tregs
(iTregs) has considerable significance in preventing asthma if generated early enough in …