Hypothalamic and genetic obesity in experimental animals: an autonomic and endocrine hypothesis.
GA Bray, DA York - Physiological reviews, 1979 - journals.physiology.org
GA Bray, DA York
Physiological reviews, 1979•journals.physiology.orgThis review compares and contrasts several types of experimental obesity, with an emphasis
on those found primarily in rodents. There are a number of different animals, so-called
“model states,” in which obesity is a major component. These are listed in Table 1 by an
etiologic classification. The major emphasis of this review is on those types of obesity
produced by hypothalamic injury and those transmitted genetically. Our discussion of
hypothalamic obesity could take many points of departure and move in one of several …
on those found primarily in rodents. There are a number of different animals, so-called
“model states,” in which obesity is a major component. These are listed in Table 1 by an
etiologic classification. The major emphasis of this review is on those types of obesity
produced by hypothalamic injury and those transmitted genetically. Our discussion of
hypothalamic obesity could take many points of departure and move in one of several …
This review compares and contrasts several types of experimental obesity, with an emphasis on those found primarily in rodents. There are a number of different animals, so-called “model states,” in which obesity is a major component. These are listed in Table 1 by an etiologic classification. The major emphasis of this review is on those types of obesity produced by hypothalamic injury and those transmitted genetically.
Our discussion of hypothalamic obesity could take many points of departure and move in one of several directions. It could focus on the behavioral aspects of the obese animals, since all obesity results from an excess intake of energy relative to energy expenditure. Since energy is obtained from food, and the ingestion of food is a behavioral process, this would be a rational approach and has been taken by some recent reviews in this field (150, 404, 585, 600).
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