Cytogenetic characterization of the human prostate cancer cell line P69SV40T and its novel tumorigenic sublines M2182 and M15

C Jackson-Cook, V Bae, W Edelman… - Cancer genetics and …, 1996 - Elsevier
Cytogenetic studies of a SV40T antigen immortalized human prostate epithelial cell line
(P69SV40T) and its increasingly tumorigenic tumor sublines, designated M2182 and M15,
were done with GTG-banding and multicolor fluorescence in situ hybridization (FISH). The
parental line and each of the two sublines were near-diploid and contained several
consistent abnormalities. Two structural chromosome anomalies were noted in all three
lines; a der (7) t (5; 20; 7) and a der (5) t (5; 9). Abnormalities that were acquired and …