[PDF][PDF] Inflammatory tales of liver cancer
Cancer Cell, 2007•cell.com
Cell culture studies have established NF-κB's critical role in cancer cell survival and
proliferation and led to the clinical use of NF-κB inhibitors. However, a paper in this issue of
Cancer Cell reveals an anticancer function for NF-κB in a mouse model where NF-κB activity
is lost specifically in hepatocytes. These studies suggest careful examination of NF-κB
inhibitors as a therapeutic modality for cancer.
proliferation and led to the clinical use of NF-κB inhibitors. However, a paper in this issue of
Cancer Cell reveals an anticancer function for NF-κB in a mouse model where NF-κB activity
is lost specifically in hepatocytes. These studies suggest careful examination of NF-κB
inhibitors as a therapeutic modality for cancer.
Cell culture studies have established NF-κB's critical role in cancer cell survival and proliferation and led to the clinical use of NF-κB inhibitors. However, a paper in this issue of Cancer Cell reveals an anticancer function for NF-κB in a mouse model where NF-κB activity is lost specifically in hepatocytes. These studies suggest careful examination of NF-κB inhibitors as a therapeutic modality for cancer.
cell.com